Well my HIV course is coming along well. We are learning so much. The questions of the week are very interesting. I had the chance to sit down and talk to friends and family about HIV and I found ot how some of them were still very uneducated or very immunture about the matter. (My brother in law to be specific) I have been learning about viral loads and counts and such. I am still as excited about this class as I was when I started.
Did you know?
Drug Cocktail! They are trying to find many different ways to activate the virus and kill it. Although the virus is known to camouflage it’s self in the “resting” immune cells. Although researchers have come up with several methods they can’t agree on which method is most affective and could give them the highest probably of successfully reaching their goal of a cure. Although, finding a cure may seem like an impossible task it is still their primary objective says Douglas Richman, the director of the Center for AIDS Research at the University of California, Dan Diego.
What is being called a Drug Cocktail is actually a highly active antiretroviral treatment as known as (HAART), which have made the virus less lethal over the last few years. However, researchers have not successfully come up with an antidote that will successfully remove the virus from the body. Robert Siliciano of the Howard Hughes Medical Institute and John Hopkins University School of Medicine who studies the replication of the virus says that when the patient discontinues the use of the drug cocktails then the virus resurfaces. See the virus usually hides it’s self for years in the CD4 T cells which usually has the ability to detect foreign bacteria, yet HIV stays in hiding for years then surfaces one day when the CD4 cells recognize the virus. Then the virus replicates with all the treatments they named from methylation, HDACs, prostratin but all of them have pros and cons.
While I don’t think that an HIV cure is impossible, I think that it will take researchers a lot longer to successfully find the cure. I have faith that it will happen one day then the only thing that will make the biggest difference will be the rather or not people are going to be will to try the drug. I know that if I had HIV and someone was offering up a cure then I would be more than willing to try it. Besides the only thing the drug could give me is side effects. Now I do not think that people will ever be open to a vaccination for HIV, I mean we have all seen the movies where everyone takes a vaccination then there is a major deadly out break or everyone turns into zombies. All and all I believe in a cure and hope they theses guts will not give up on their research and I pray they continue to have the funding. It will happen one day and a lot of lives will be saved.
If you are interested in the article it is at this address http://www.scientificamerican.com/article.cfm?id=hiv-aids-latent-reservoir-treatment-cure
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I'm sorry, Latora. The green on the pink background is so hard on my eyes to read. Can you please use black on the pink background, or change the background to something pink will go with easier.
ReplyDeleteCD4 cells don't detect the presence of the virus, that job belongs to the macrophage. CD4 is responsible for turning on the killer T cells and the B cells. Yes, HIV can hide in the proviral state in resting CD4 cells and then when that cell switches on, it will begin to produce HIV.
If you are researching drugs and HIV then this post is your Did You Know post. Where is your regular blog on how you are progressing is this class? It is to be part of your weekly blog. I don't want to see separate blogs for each item, I want them all in one long blog.
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